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Uterine Fibroids

(Fibroids; Leiomyoma; Myoma; Fibromyoma)

Definition

Fibroids are benign (noncancerous) growths in the wall of the uterus. The uterus is the organ where a fetus grows during pregnancy.
Fibroids are common. They may be very small or they could grow to eight or more inches in diameter. Most fibroids remain inside the uterus. In rare cases, they may stick out and affect nearby organs. It is common for there to be more than one fibroid.
Uterine Fibroid
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Causes

The cause of fibroids is unknown.
Fibroid growth is stimulated by female reproductive hormones. As a result:
Genetics may make some women more prone to fibroids. Substances that control blood vessel growth may also affect fibroid growth.

Risk Factors

Certain factors affect your risk of fibroids, for example:
  • Risk increase with age until menopause
  • African American women have increased risk of fibroids
  • Family history
Obesity and high blood pressure may also be linked to fibroids.

Symptoms

Symptoms range from none at all to mild or severe. This depends on the size and location of the growths.
Symptoms may include:
  • Pelvic pain
  • Feeling of pelvic pressure
  • Heavy menstrual bleeding
  • Clots in menstrual flow
  • Long periods
  • Bleeding between periods
  • Increased cramping during periods
  • Pain during sex
  • Frequent need to urinate
  • Constipation
  • Bloating
  • Enlarged uterus (giving the appearance of pregnancy)
  • Low back or leg pain
  • Infertility by blocking the fallopian tubes
  • Miscarriage
Iron-deficiency anemia may develop if bleeding is heavy. This is low levels of red blood cells. It will affect the amount of oxygen your blood can carry.

Diagnosis

Doctors find most fibroids during routine pelvic exams.
To confirm the diagnosis, your doctor may want to get a detailed picture of the fibroid. This may be taken with one or more of the following tests:

Treatment

Most women with fibroids have no symptoms and do not need treatment. Your doctor may recommend "watchful waiting". During this period your doctor will monitor any changes on a regular basis. Treatment may be done later if needed.
Treatments include:

Pain Medication

Your doctor may recommend:
  • Over-the-counter pain relievers to ease mild symptoms
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) to reduce inflammation and relieve cramping
  • Prescription pain medicine—If pain cannot be managed with medications above

Hormonal Therapy

Hormone medicines may be an option if you are not trying to become pregnant. These drugs can shrink fibroids and lessen pain. However, fibroids can return once you stop taking the drugs. These drugs may be used to make fibroids smaller just before surgery.

Procedures

Surgery may be considered if:
  • The uterus becomes extremely large
  • The fibroids are interfering with fertility
  • Symptoms are severe
Surgical procedures include:
  • Myomectomy —An incision is made in the abdomen. The fibroids are removed from the uterus.
  • Hysterectomy —The entire uterus is removed. You will be unable to have children if you have this surgery.
Other options include:
Other options include:
  • Uterine fibroid ablation—This is a minimally invasive procedure. It blocks blood flow to the fibroids. This will make the fibroids shrink.
  • Focused ultrasound therapy—Energy is centered on the fibroid to destroy it. This procedure may not be ideal for patients who are very overweight, have very large fibroids, or have extensive scars from prior abdominal surgeries.
If you are diagnosed with uterine fibroids, follow your doctor's instructions .

Prevention

There are no guidelines for preventing fibroids.

RESOURCES

The American Congress of Obstetricians and Gynecologists http://www.acog.org/

The International Council on Infertility Information Dissemination http://www.inciid.org/

CANADIAN RESOURCES

The Society of Obstetricians and Gynaecologists of Canada http://www.sogc.org/

Women's Health Matters http://www.womenshealthmatters.ca/

References

Fibroids. Healthy Women website. Available at: http://www.healthywomen.org/condition/fibroids . Updated September 8, 2008. Accessed December 7, 2012.

Uterine fibroid embolization (UFE). RadiologyInfo.org website. Available at: http://www.radiologyinfo.org/en/info.cfm?pg=ufe . Updated April 24, 2012. Accessed August 23, 2012.

Uterine fibroids. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed/ . Updated May 22, 2012. Accessed August 23, 2012.

Uterine fibroids. Focused Ultrasound Foundation website. Available at: http://www.fusfoundation.org/Uterine-Fibroids/uterine-fibroids . Updated May 8, 2012. Accessed August 23, 2012.

Revision Information

  • Reviewer: Andrea Chisholm
  • Review Date: 09/2012 -
  • Update Date: 09/10/2012 -

This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.

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